KPC-2-IN-3 (Compound 3b) is a KPC-2 inhibitor with IC50 of 0.533 µM and Kiof 0.194 µM. KPC-2-IN-3 has an antimicrobial activity against carbapenem-resistant K. pneumonia K47-25 and reduces bacterial count with a postantibiotic effect in synergy with Meropenem (HY-13678). KPC-2-IN-3 significantly reduces lung bacterial load in a murine pneumonia model[1].
Molekulargewicht:
245.94
Formel:
C8H9BFO5P
Target-Kategorie:
Bacterial
Anwendungsbeschreibung:
MCE Product type: Reference compound
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
