EGFR-IN-12, CAS [[879127-07-8]]

Produktübersicht

• Artikelname: EGFR-IN-12, CAS [[879127-07-8]]
• Artikelnummer: MCE-HY-17499
• Hersteller Artikelnummer: HY-17499
• Alternativnummer: MCE-HY-17499-50MG,MCE-HY-17499-100MG,MCE-HY-17499-10MMX1ML,MCE-HY-17499-25MG,MCE-HY-17499-10MG,MCE-HY-17499-5MG,MCE-HY-17499-1MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

EGFR-IN-12 is a 4,6-disubstituted pyrimidine and is a potent, ATP-competitive, irreversible and highly selective EGFR inhibitor with an IC50of 21 nM. EGFR-IN-12 also inhibits mutant EGFRL858R and EGFRL861Q with IC50s of 63 nM and 4 nM, respectively. EGFR-IN-12 displays strong selectivity for EGFR over HER4 (IC50 = 7640 nM) and a panel of 55 other kinases. EGFR-IN-12 induces cells apoptosis and has antitumor activity[1][2].

Produkteigenschaften

• Molekulargewicht: 413.40
• Reinheit: 99.60
• CAS Nummer: [879127-07-8]
• Formel: C21H18F3N5O
• Target-Kategorie: Apoptosis,EGFR

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound