GPX4-IN-18, CAS [[3016433-00-1]] Preis auf Anfrage

Produktübersicht

• Artikelname: GPX4-IN-18, CAS [[3016433-00-1]] Preis auf Anfrage
• Artikelnummer: MCE-HY-175041
• Hersteller Artikelnummer: HY-175041
• Alternativnummer: MCE-HY-175041-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

GPX4-IN-18 (Compound 17) is a ferrocene-containing inhibitor of glutathione peroxidase 4 (GPX4). GPX4-IN-18 is also an inducer of ferroptosis. GPX4-IN-18 can increase the production of ROS and malondialdehyde (MDA) levels in OS-RC-2 clear cell renal cell carcinoma cells. GPX4-IN-18 induces ferroptosis in HT-1080 cells with IC50s of 0.007 µM (absence of ferrostatin-1) and 1.486 µM (presence of ferrostatin-1). GPX4-IN-18 reduces in vivo tumor volume and intratumoral GPX4 levels in OS-RC-2 xenograft murine model[1].

Produkteigenschaften

• Molekulargewicht: 554.84
• CAS Nummer: [3016433-00-1]
• Formel: C30H27ClFeN2O3
• Target-Kategorie: Cannabinoid Receptor,Ferroptosis,Glutathione Peroxidase,Reactive Oxygen Species (ROS)

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound