(3R,5R)-Rosuvastatin, CAS [[1094100-06-7]] Preis auf Anfrage
Artikelnummer:
MCE-HY-17504C
Hersteller Artikelnummer:
HY-17504C
Alternativnummer:
MCE-HY-17504C-1UNIT
Hersteller:
MedchemExpress
Kategorie:
Biochemikalien
(3R,5R)-Rosuvastatin is the (3R,5R)-enantiomer of Rosuvastatin. Rosuvastatin is a competitive HMG-CoA reductase inhibitor with an IC50 of 11 nM[1]. Rosuvastatin potently blocks human ether-a-go-go related gene (hERG) current with an IC50 of 195 nM[2]. Rosuvastatin reduces the expression of the mature hERG and the interaction of heat shock protein 70 (Hsp70) with the hERG protein. Rosuvastatin is very effective in lowering low-density lipoprotein (LDL) cholesterol, triglycerides, and C-reactive protein levels[3].
