Itraconazole, CAS [[84625-61-6]] Preis auf Anfrage
Artikelnummer:
MCE-HY-17514
Hersteller Artikelnummer:
HY-17514
Alternativnummer:
MCE-HY-17514-500MG,MCE-HY-17514-100MG
Hersteller:
MedchemExpress
Kategorie:
Biochemikalien
Alternative Synonym:
R51211
Itraconazole (R51211) is a triazole antifungal agent and a potent and orally active Hedgehog (Hh) signaling pathway antagonist with an IC50 of ~800 nM. Itraconazole potently inhibits lanosterol 14alpha-demethylase (cytochrome P450 enzyme), thereby inhibits the oxidative conversion of lanosterol to ergosterol. Itraconazole has anticancer and antiangiogenic effects. Itraconazole is a oxysterol-binding protein (OSBP) inhibitor[1][2][3][4].