LSD1-IN-44 (Compound 19) is a LSD1 inhibitor with an IC50 of 0.02 µM for LSD1-CoREST enzymatic complex. LSD1-IN-44 has significant antischistosomal activity against transformed schistosomula (NTS) and Schistosoma mansoni adult worms while showing a delayed onset of action towards juvenile forms. LSD1-IN-44 has no significant toxicity to human cells. LSD1-IN-44 can be used for schistosomiasis research[1].
Molekulargewicht:
352.86
Formel:
C21H21ClN2O
Target-Kategorie:
Histone Demethylase
Anwendungsbeschreibung:
MCE Product type: Reference compound
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