DEL-S1 is a SLIT2 binder. DEL-S1 significantly inhibits the formation of the SLIT2/ROBO1 complex by inducing conformational rearrangement, and further suppresses its function, with an IC50 of 68.8 µM. DEL-S1 can be used in studies of neurodevelopment, immunomodulation, and cancers such as glioblastoma[1].
Molekulargewicht:
534.66
Reinheit:
98.50
Formel:
C27H38N10O2
Target-Kategorie:
Slit Proteins
Anwendungsbeschreibung:
MCE Product type: Reference compound
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