GlcNAc-MurNAc, CAS [[41137-10-4]] Preis auf Anfrage
Artikelnummer:
MCE-HY-175222
Hersteller Artikelnummer:
HY-175222
Alternativnummer:
MCE-HY-175222-25MG,MCE-HY-175222-50MG
Hersteller:
MedchemExpress
Kategorie:
Biochemikalien
GlcNAc-MurNAc, a disaccharide, is a TLR4 agonist with a Kd of 383 µM for murine TLR4. GlcNAc-MurNAc directly binds to TLR4 and activates its downstream NF-kappaB and IRF pathways. GlcNAc-MurNAc improves Dextran sulfate sodium salt (DSS) (HY-116282C)-induced colitis in mice through a TLR4-dependent mechanism. GlcNAc-MurNAc can be used for the study of inflammatory bowel disease[1].