JWJ-01-378 Preis auf Anfrage
Artikelnummer:
MCE-HY-175271
| Artikelname: |
JWJ-01-378 Preis auf Anfrage |
| Artikelnummer: |
MCE-HY-175271 |
| Hersteller Artikelnummer: |
HY-175271 |
| Alternativnummer: |
MCE-HY-175271-1UNIT |
| Hersteller: |
MedchemExpress |
| Kategorie: |
Biochemikalien |
| JWJ-01-378 is a selective TRK PROTAC degrader. JWJ-01-378 efficiently degrades WT TRK and TPM3-TRKA fusion proteins and inhibits downstream pERK signaling, while showing limited efficacy against TRK inhibitor resistant mutants and ALK fusions. JWJ-01-378 potently suppresses cancer cell proliferation[1].Pink: TRK ligand (HY-160520), Blue: CRBN ligase ligand (HY-103596), Black: linker |
| Molekulargewicht: |
1045.14 |
| Formel: |
C55H62F2N10O9 |
| Target-Kategorie: |
ERK,PROTACs,Trk Receptor |
| Anwendungsbeschreibung: |
MCE Product type: Reference compound |
