ASX-173, CAS [[2748800-08-8]] Preis auf Anfrage

Produktübersicht

• Artikelname: ASX-173, CAS [[2748800-08-8]] Preis auf Anfrage
• Artikelnummer: MCE-HY-175282
• Hersteller Artikelnummer: HY-175282
• Alternativnummer: MCE-HY-175282-50MG,MCE-HY-175282-25MG,MCE-HY-175282-10MG,MCE-HY-175282-5MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

ASX-173 is an orally active inhibitor of asparagine synthetase (ASNS) (IC50 = 0.113 µM, Ki = 0.4 nM). ASX-173 enhances the anticancer activity of L-asparaginase (ASNase) (HY-P1923). ASX-173 disrupts nucleotide synthesis and induces leukemia cell cycle arrest, apoptosis and autophagy in leukemia cells in combination with ASNase. ASX-173 slows the growth of OCI-AML2 xenografts in combination with ASNase. ASX-173 is indicated for the study of acute lymphoblastic leukemia, acute myeloid leukemia, colorectal cancer, and other cancers[1].

Produkteigenschaften

• Molekulargewicht: 475.55
• CAS Nummer: [2748800-08-8]
• Formel: C28H30FN3O3
• Target-Kategorie: Akt,Apoptosis,Atg8/LC3,Autophagy,Caspase,CDK,PARP

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound