NOTA-IMB-RGD is a dual molecular probe targeting integrin alphavbeta3 and programmed death ligand-1 (PD-L1). NOTA-IMB-RGD blocks the PD-1/PD-L1 signaling pathway and integrin alphavbeta3-overexpressing tumor vasculature. NOTA-IMB-RGD is promising for research of solid tumors co-expressing PD-L1 and alphavbeta3 (e.g., glioma, breast cancer)[1].
Molekulargewicht:
2659.06
Formel:
C118H196N30O37S
Target-Kategorie:
Integrin,PD-1/PD-L1
Anwendungsbeschreibung:
MCE Product type: Reference compound
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