Acid Ceramidase-IN-3, CAS [[2907705-12-6]] Preis auf Anfrage

Produktübersicht

• Artikelname: Acid Ceramidase-IN-3, CAS [[2907705-12-6]] Preis auf Anfrage
• Artikelnummer: MCE-HY-175496
• Hersteller Artikelnummer: HY-175496
• Alternativnummer: MCE-HY-175496-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

Acid Ceramidase-IN-3 is a acid ceramidase (aCDase) inhibitor. Acid Ceramidase-IN-3 inhibits the enzymatic activity of aCDase with a pIC 50 of 8.5 in enzymatic assays and 6.8 in A375 melanoma cellular assays. Acid Ceramidase-IN-3 promotes HSC inactivation, as measured by a dose-dependent reduction in COL1A1 and ACTA2. Acid Ceramidase-IN-3 inhibits aCDase activity in HSCs, promotes HSC inactivation and suppresses YAP/TAZ nuclear localization. Acid Ceramidase-IN-3 increases Dynein/Kinesin (NDE1, NDEL1. KIF3B, KIF15) while decreases several proteins involved with signaling pathway (SARM1, RGAP1, PDGF-D,PDGFR-B). Acid Ceramidase-IN-3 can be used for the study of fibrotic diseases[1].

Produkteigenschaften

• Molekulargewicht: 443.51
• CAS Nummer: [2907705-12-6]
• Formel: C27H26FN3O2
• Target-Kategorie: Ceramidase

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound