Tubulin-IN-54 is a tubulin inhibitor. Tubulin-IN-54 exhibits anti-proliferative activity against various cancer cells. Tubulin-IN-54 inhibits tubulin polymerization, disrupts microtubule networks, induces G2/M cell cycle arrest, and promotes cancer cell apoptosis. Tubulin-IN-54 demonstrates significant anti-tumor efficacy in mice bearing PC-3/TxR xenografts. Tubulin-IN-54 can be used for the study of taxane-resistant cancers (prostate cancer, melanoma)[1].
Molekulargewicht:
377.39
Formel:
C21H19N3O4
Target-Kategorie:
Apoptosis,Microtubule/Tubulin
Anwendungsbeschreibung:
MCE Product type: Reference compound
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