EVT0185, CAS [[2588489-03-4]] Preis auf Anfrage

Produktübersicht

• Artikelname: EVT0185, CAS [[2588489-03-4]] Preis auf Anfrage
• Artikelnummer: MCE-HY-175606
• Hersteller Artikelnummer: HY-175606
• Alternativnummer: MCE-HY-175606-25MG,MCE-HY-175606-10MG,MCE-HY-175606-100MG,MCE-HY-175606-5MG,MCE-HY-175606-50MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

EVT0185 is an orally active ATP citrate lyase (ACLY) inhibitor. EVT0185 is converted to a CoA thioester in the liver by SLC27A2 and interacts with the CoA-binding site of ACLY. EVT0185-CoA inhibits ACLY activity with an IC50 of 2.5 µM. EVT0185 can phenocopy the immune and antitumour effects of genetic ACLY deletion. EVT0185 can increase tumour-infiltrating B cells and chemokine CXCL13 levels. EVT0185 can be used for the research of cancer, such as hepatocellular carcinoma (HCC)[1].

Produkteigenschaften

• Molekulargewicht: 362.50
• Reinheit: 98.97
• CAS Nummer: [2588489-03-4]
• Formel: C22H34O4
• Target-Kategorie: ATP Citrate Lyase

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound