LATS1/2-IN-1, CAS [[3024011-99-9]] Preis auf Anfrage

Produktübersicht

• Artikelname: LATS1/2-IN-1, CAS [[3024011-99-9]] Preis auf Anfrage
• Artikelnummer: MCE-HY-175649
• Hersteller Artikelnummer: HY-175649
• Alternativnummer: MCE-HY-175649-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

LATS1/2-IN-1 is a potent and selective LATS1 and LATS2 inhibitor. LATS1/2-IN-1 exhibits potent inhibitory activity against LATS1 and LATS2 with IC50 values of 4.4 nM and 5.5 nM as determined via r33P functional assay. LATS1/2-IN-1 displays cellular IC50 values of 136 nM for LATS1 and 36.0 nM for LATS2 as determined via NanoBRET assay. LATS1/2-IN-1 reduces phosphorylation of YAP1 in mouse liver. LATS1/2-IN-1 demonstrates wound healing activity in HT-1080 scratch assay and in vivo SKH1 mouse punch biopsy model. LATS1/2-IN-1 can be used for the study of regenerative medicine indications such as wound healing[1].

Produkteigenschaften

• Molekulargewicht: 503.60
• CAS Nummer: [3024011-99-9]
• Formel: C26H31F2N3O3S
• Target-Kategorie: YAP

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound