STAT6-IN-9 is a potent STAT6 inhibitor with an EC50 value of 4 nM. STAT6-IN-9 effectively blocks STAT6 activation mediated by the IL-13-IL-13 receptor/IL-4 receptor pathway. STAT6-IN-9 inhibits CCL17 secretion with an IC50 value of 4.6 nM. STAT6-IN-9 can be used to investigate various chronic inflammatory diseases mediated by STAT6, such as allergy, asthma, and chronic obstructive pulmonary disease[1].
Molekulargewicht:
568.67
Reinheit:
98.11
CAS Nummer:
[3092076-15-5]
Formel:
C31H36N8O3
Target-Kategorie:
Interleukin Related,STAT
Anwendungsbeschreibung:
MCE Product type: Reference compound1
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