AChE/BChE-IN-29 is an AChE/BChE inhibitor. AChE/BChE-IN-29 exhibits balanced dual cholinesterase inhibitory activity with IC50 values of 2.1 µM for Electrophorus electricus AChE (eeAChE) and 6.3 µM for equine serum butyrylcholinesterase (eqBChE). AChE/BChE-IN-29 effectively inhibits amyloid-beta (Abeta42) aggregation and tau protein aggregation in E. coli cell models. AChE/BChE-IN-29 can be used for the study of Alzheimers disease (AD)[1].
Molekulargewicht:
364.78
Formel:
C21H13ClO4
Target-Kategorie:
Amyloid-beta,Cholinesterase (ChE),Tau Protein
Anwendungsbeschreibung:
MCE Product type: Reference compound
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