PRMT1-IN-3, CAS [[892570-48-8]] Preis auf Anfrage

Produktübersicht

• Artikelname: PRMT1-IN-3, CAS [[892570-48-8]] Preis auf Anfrage
• Artikelnummer: MCE-HY-175821
• Hersteller Artikelnummer: HY-175821
• Alternativnummer: MCE-HY-175821-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

PRMT1-IN-3 is a potent protein arginine methyltransferase 1 (PRMT1) inhibitor with an IC50 of 4.11 µM. PRMT1-IN-3 inhibits PRMT6 and PRMT8 with IC50s of 23.3 and 30.1 µM. PRMT1-IN-3 suppresses asymmetric dimethylarginine (ADMA) levels and histone H4R3me2a modification in triple-negative breast cancer (TNBC) cells. PRMT1-IN-3 induces cell cycle arrest, apoptosis, and inhibits migration and colony formation in MDA-MB-231 cells. PRMT1-IN-3 acts as chemotherapeutic sensitizers for Paclitaxel (HY-B0015). PRMT1-IN-3 can be used for the study of TNBC[1].

Produkteigenschaften

• Molekulargewicht: 302.39
• CAS Nummer: [892570-48-8]
• Formel: C18H23FN2O
• Target-Kategorie: Apoptosis,Histone Methyltransferase

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound