Ferroptosis-IN-22, CAS [[3096878-87-1]]

Produktübersicht

• Artikelname: Ferroptosis-IN-22, CAS [[3096878-87-1]]
• Artikelnummer: MCE-HY-175869
• Hersteller Artikelnummer: HY-175869
• Alternativnummer: MCE-HY-175869-10MG,MCE-HY-175869-25MG,MCE-HY-175869-5MG,MCE-HY-175869-50MG,MCE-HY-175869-10MMX1ML
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

Ferroptosis-IN-22 is a selective ferroptosis inhibitor by targeting NCOA4 and disrupting its interaction with ferritin with an EC50 of 520 nM and a Kd of 0.78 µM. Ferroptosis-IN-22 has a strong inhibitory activity against ferroptosis induced by multiple ferroptosis inducers (RSL3 (HY-100218A), Erastin (HY-15763), ML210 (HY-100003), FIN56 (HY-103087)), but does not inhibit necrosis induced by H2O2 or apoptosis induced by STS (HY-15141). Ferroptosis-IN-22 effectively ameliorates Concanavalin A (HY-P2149)-induced acute liver injury. Ferroptosis-IN-22 can be used for the study of ferroptosis-related diseases[1].

Produkteigenschaften

• Molekulargewicht: 393.48
• Reinheit: 99.97
• CAS Nummer: [3096878-87-1]
• Formel: C27H23NO2
• Target-Kategorie: Ferroptosis

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound