PROTAC STING degrader-4 Preis auf Anfrage

Produktübersicht

• Artikelname: PROTAC STING degrader-4 Preis auf Anfrage
• Artikelnummer: MCE-HY-176180
• Hersteller Artikelnummer: HY-176180
• Alternativnummer: MCE-HY-176180-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

PROTAC STING degrader-4 is a nitro-free covalent STING PROTAC degrader with a DC50 of 3.23 µM. PROTAC STING degrader-4 effectively inhibits STING as well as its downstream signaling, such as p-TBK1 and p-NF-kappaB (p-P65), and immune-inflammatory cytokines. PROTAC STING degrader-4 mitigates kidney and blood inflammation in Cisplatin (HY-17394)-induced acute kidney injury (AKI) mice model[1]. Pink: STING ligand (HY-176183), Blue: CRBN ligase ligand (HY-103596), Black: linker (HY-176182), CRBN ligase ligand + linker: HY-176181

Produkteigenschaften

• Molekulargewicht: 837.70
• Formel: C39H42Cl2N8O9
• Target-Kategorie: IKK,NF-kappaB,PROTACs,STING

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound1