MAO-B-IN-45, CAS [[3069915-36-9]] Preis auf Anfrage

Produktübersicht

• Artikelname: MAO-B-IN-45, CAS [[3069915-36-9]] Preis auf Anfrage
• Artikelnummer: MCE-HY-176271
• Hersteller Artikelnummer: HY-176271
• Alternativnummer: MCE-HY-176271-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

MAO-B-IN-45 is a dual inhibitor of ferroptosis and MAO-B. MAO-B-IN-45 shows selectivity towards MAO-B with an IC50 of 87.47 nM and selectivity exceeding 229-fold for MAO-B over MAO-A. MAO-B-IN-45 has excellent antiferroptosis activity through modulation of the iron metabolic pathway and GSH-GPX4 axis in vitro. MAO-B-IN-45 improves cognitive and behavioral impairments in 3*Tg (APP/Tau/Ps1) AD mouse and significantly reduced the levels of ferritin heavy chain 1 (FTH1), APP, and Tau phosphorylation (p-Tau) proteins in the brain[1].

Produkteigenschaften

• Molekulargewicht: 315.75
• CAS Nummer: [3069915-36-9]
• Formel: C17H14ClNO3
• Target-Kategorie: Amyloid-beta,Ferroptosis,Glutathione Peroxidase,Monoamine Oxidase,Reactive Oxygen Species (ROS),Tau Protein

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound1