RORgammat inverse agonist 35 (Compound 22) is a RORgammat inverse agonist with an IC50 of 1.51 µM. RORgammat inverse agonist 35 significantly inhibits Th17 differentiation and proinflammatory properties in human CD4+ T cells. RORgammat inverse agonist 35 can be used for research of Th17-driven autoimmune diseases, such as psoriasis, multiple sclerosis, and inflammatory bowel disease (IBD)[1].
Molekulargewicht:
450.53
Formel:
C25H23FN2O3S
Target-Kategorie:
Interleukin Related,ROR
Anwendungsbeschreibung:
MCE Product type: Reference compound1
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