PROTAC pan-KRAS degrader-1, CAS [[3043908-63-7]] Preis auf Anfrage

Artikelnummer: MCE-HY-176489
Artikelname: PROTAC pan-KRAS degrader-1, CAS [[3043908-63-7]] Preis auf Anfrage
Artikelnummer: MCE-HY-176489
Hersteller Artikelnummer: HY-176489
Alternativnummer: MCE-HY-176489-1UNIT
Hersteller: MedchemExpress
Kategorie: Biochemikalien
PROTAC pan-KRAS degrader-1 is a pan-KRAS PROTAC degrader for degrading different KRAS mutation types, such as G12D, G12C, G12V, and G13D. PROTAC pan-KRAS degrader-1 potently degrades KRAS mutation (G12D) in AGS cells, with a DC50 of 1.1 nM, Dmax of 95%. PROTAC pan-KRAS degrader-1 can be used to search diseases caused by KRAS mutation or amplification, especially cancers such as breast cancer, bladder cancer, gastric cancer, etc[1]. Pink: pan-KRAS ligand (HY-176490), Blue: VHL ligase ligand (HY-170353), Black: linker (HY-176491),
Molekulargewicht: 1192.38
CAS Nummer: [3043908-63-7]
Formel: C63H71F2N13O7S
Target-Kategorie: PROTACs,Ras
Anwendungsbeschreibung: MCE Product type: Reference compound