ssPalmE-P4-C2 is a SS-cleavable and pH-sensitive lipid-like material (ssPalm) with a vitamin E-scaffold. ssPalmE-P4-C2 improves gene knockdown activity against FVII with an ED50 of 0.5 mg/kg. ssPalmE-P4-C2 can be used to synthesize lipid nanoparticles (LNPs) for delivering siRNA to the hepatocyte. ssPalmE-P4-C2 can be used for the RNA therapies for dyslipidemia, hepatitis B/C infections and transthyretin amyloidosis research[1].
Molekulargewicht:
1402.15
Reinheit:
98.81
CAS Nummer:
[2247153-41-7]
Formel:
C84H140N2O10S2
Target-Kategorie:
Liposome,Ser/Thr Protease
Anwendungsbeschreibung:
MCE Product type: Oligonucleotides
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