S1PR5-IN-1 (Compound 7a) is a highly selective S1PR5 antagonist and orally bioavailable inhibitor with a human S1PR5 IC50 of 85.4 nM and human S1PR5 Ka of 2.173 nM.S1PR5-IN-1 binds to S1PR5 and inhibits natural killer cell migration toward sphingosine-1-phosphate.S1PR5-IN-1 can be used for the research of multiple sclerosis[1].
Molekulargewicht:
441.58
Reinheit:
99.58
CAS Nummer:
[3107268-28-7]
Formel:
C27H36FNO3
Target-Kategorie:
LPL Receptor
Anwendungsbeschreibung:
MCE Product type: Reference compound
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