diABZI-Mal (ABM5) is a STING agonist with a Maleimide (HY-W007324) linker, which has a EC50 of 349 nM and is applicable for conjugate synthesis. diABZI-Mal activates the cGAS-STING pathway and induces the production of cytokines, such as type I interferons. diABZI-Mal promotes the maturation of dendritic cells (DCs) and effectively induces CD8+ T cell immune responses. diABZI-Mal inhibits tumor growth[1].
Molekulargewicht:
1042.15
Reinheit:
98.02
CAS Nummer:
[2763540-24-3]
Formel:
C52H63N15O9
Target-Kategorie:
STING
Anwendungsbeschreibung:
MCE Product type: Reference compound
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