NK3R-IN-2 is an orally active NK3R inhibitor with an IC50 of 330.50 nM for human NK3R. NK3R-IN-2 can pass through the blood-brain barrier. NK3R-IN-2 has excellent NK3R binding affinity (IC50 = 87.31 nM) in CHO-K1 cells. NK3R-IN-2 effectively inhibits the level of luteinizing hormone (LH). NK3R-IN-2 can be used for research on hormone related conditions[1].
Molekulargewicht:
416.86
Formel:
C18H14ClFN6OS
Target-Kategorie:
Neurokinin Receptor
Anwendungsbeschreibung:
MCE Product type: Reference compound
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