CDK9-IN-40 is a potent and orally active CDK9 inhibitor with an IC50 of 5.5 nM. CDK9-IN-40 shows high selectivity for CDK9 versus CDK1, CDK2, CDK4, and CDK6, respectively. CDK9-IN-40 can arrest cell cycle, induce cell apoptosis and inhibit tumor growth. CDK9-IN-40 exhibits strong anti-cancer activity[1].
Molekulargewicht:
422.55
Formel:
C21H26N8S
Target-Kategorie:
Apoptosis,CDK
Anwendungsbeschreibung:
MCE Product type: Reference compound
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