PROTAC Bcl-xL degrader-4, CAS [[2930759-37-6]] Preis auf Anfrage
Artikelnummer:
MCE-HY-176740
| Artikelname: |
PROTAC Bcl-xL degrader-4, CAS [[2930759-37-6]] Preis auf Anfrage |
| Artikelnummer: |
MCE-HY-176740 |
| Hersteller Artikelnummer: |
HY-176740 |
| Alternativnummer: |
MCE-HY-176740-1UNIT |
| Hersteller: |
MedchemExpress |
| Kategorie: |
Biochemikalien |
| PROTAC Bcl-xL degrader-4 (Compound 2-38-III) is a Bcl-xL PROTAC degrader. PROTAC Bcl-xL degrader-4 has strong anti-tumor activity against HepG2 cells and HUVEC cells. PROTAC Bcl-xL degrader-4 induces cells apoptosis by decreasing mitochondrial membrane potential and activating the MAPK signaling pathway. PROTAC Bcl-xL degrader-4 significantly inhibits tumor growth in xenograft tumor mouse models[1]. Pink: MAPK ligand (HY-176741), Blue: CRBN ligase ligand (HY-10984), Black: linker (HY-W017440) |
| Molekulargewicht: |
702.71 |
| CAS Nummer: |
[2930759-37-6] |
| Formel: |
C39H34N4O9 |
| Target-Kategorie: |
Apoptosis,Bcl-2 Family,ERK,JNK,Mitochondrial Metabolism,p38 MAPK,PROTACs,Reactive Oxygen Species (ROS) |
| Anwendungsbeschreibung: |
MCE Product type: Reference compound |
