SW016789 is a hypersecretion-inducer targeting VDAC1. SW016789 can induce insulin hypersecretion and Ca2+ influx in beta-cells directly. SW016789 induces a transient endoplasmic reticulum stress response (ER stress), but does not cause beta cell death. SW016789 has reversible and non-apoptotic characteristics. SW016789 can be used for the study of Diabetes mellitus type 2 (T2DM) beta-cell dysfunction[1][2].
Molekulargewicht:
349.45
Reinheit:
99.85
CAS Nummer:
[292613-04-8]
Formel:
C20H19N3OS
Target-Kategorie:
VDAC
Anwendungsbeschreibung:
MCE Product type: Reference compound
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