VVD-442 is an inhibitor targeting PI3Kalpha. VVD-442 covalently binds to Cys242 in the RAS-binding domain of PI3K p110alpha, induces conformational changes, and disrupts the interaction between PI3K p110alpha and RAS proteins. VVD-442 also blocks RAS-mediated PI3K activation. VVD-442 can be used in research related to RAS-mutant cancers and HER2-overexpressing cancers[1].
Molekulargewicht:
607.94
Reinheit:
99.97
CAS Nummer:
[3055318-88-9]
Formel:
C23H25BrClFN2O5S2
Target-Kategorie:
Akt,PI3K,Ras
Anwendungsbeschreibung:
MCE Product type: Reference compound1
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten