NLRP3 modulator 8, CAS [[3069891-88-6]] Preis auf Anfrage
Artikelnummer:
MCE-HY-177433
Hersteller Artikelnummer:
HY-177433
Alternativnummer:
MCE-HY-177433-1UNIT
Hersteller:
MedchemExpress
Kategorie:
Biochemikalien
NLRP3 modulator 8 (Compound 14) is a NLRP3 modulator. NLRP3 modulator 8 significantly degrades NEK7 with an DC50 of 9 nM. NLRP3 modulator 8 dose-dependently inhibits caspase-1 activity and IL-1beta release in macrophages in response to NLRP3 inflammasome activation. NLRP3 modulator 8 can be used for autoinflammatory and autoimmune disorders like multiple sclerosis, neurodegeneraive diseases like Alzheimers disease and cardiovascular and melabolic disorders like pericarditis and Type 2 diabetes research[1].
