MeThPmR, a ribonucleoside derivative, is a potent and selective human nucleoside transporter 1 (hCNT1) inhibitor (Ki/sub> = 0.16-0.69 µM). MeThPmR exhibit weak inhibitory activity on hCNT2 (IC50 = 360 µM) and hCNT3 (Ki = 4.7 µM). MeThPmR can protect cells from the toxicity of nucleoside drugs. MeThPmR can be used for the research of cancer[1].
Molekulargewicht:
298.31
CAS Nummer:
[1262032-38-1]
Formel:
C12H14N2O5S
Target-Kategorie:
Nucleoside Transporters
Anwendungsbeschreibung:
MCE Product type: Oligonucleotides
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