dMeThPmR, a ribonucleoside derivative, is a potent and selective human nucleoside transporter 1 (hCNT1) inhibitor (Ki = 0.3-0.98 µM). dMeThPmR exhibit weak inhibitory activity on hCNT2 (IC50 = 133 µM) and hCNT3 (Ki = 32.7 µM). dMeThPmR can protect cells from the toxicity of nucleoside drugs. dMeThPmR can be used for the research of cancer[1].
Molekulargewicht:
282.32
CAS Nummer:
[1262032-37-0]
Formel:
C12H14N2O4S
Target-Kategorie:
Nucleoside Transporters
Anwendungsbeschreibung:
MCE Product type: Oligonucleotides
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