2-Deoxy-N-methyl-AMP ammonium is an N6-substituted adenine nucleotide derivative and a glycosyl donor. On one hand, 2-Deoxy-N-methyl-AMP ammonium acts as a specific substrate for N6-methyl-AMP aminohydrolase, and it is catalytically converted to dIMP to participate in the nucleotide metabolic cycle. On the other hand, 2-Deoxy-N-methyl-AMP ammonium also serves as a guanosine diphosphate (GDP)-linked fucose derivative donor, driving site-specific glycoconjugation of proteins under the mediation of alpha-1,3-fucosyltransferase. 2-Deoxy-N-methyl-AMP ammonium is an important molecular tool for investigating the mechanisms of nucleotide modification and protein glycosylation[1][2].
Molekulargewicht:
362.28
Reinheit:
99.36
Formel:
C11H19N6O6P
Target-Kategorie:
Nucleoside Antimetabolite/Analog
Anwendungsbeschreibung:
MCE Product type: Oligonucleotides
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