D574-0246, CAS [[1269110-12-4]]

Produktübersicht

• Artikelname: D574-0246, CAS [[1269110-12-4]]
• Artikelnummer: MCE-HY-178018
• Hersteller Artikelnummer: HY-178018
• Alternativnummer: MCE-HY-178018-5MG, MCE-HY-178018-10MG, MCE-HY-178018-25MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: iOXCT1

Produktbeschreibung

D574-0246 is a dual-activity inhibitor of OXCT1, inhibiting both the ketolytic and succinyltransferase activities of OXCT1. D574-0246 reduces substrate-specific (LACTB K284) and global protein succinylation and decreases OXCT1 ketolytic activity in HepG2 cells. D574-0246 inhibits the viability of HCC cells (IC50: 16.49 µM in PLC cells, 6.656 µM in HepG2 cells). D574-0246 exerts anti-tumor efficacy in nude mice bearing OXCT1-overexpressing HepG2 xenograft tumors. D574-0246 can be used for the study of hepatocellular carcinoma (HCC)[1].

Produkteigenschaften

• Molekulargewicht: 446.50
• Reinheit: 99.87
• CAS Nummer: [1269110-12-4]
• Formel: C24H26N6O3
• Target-Kategorie: Mitochondrial Metabolism

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound