SS-3091 is a pan KRas inhibitor. SS-3091 binds to the interaction interfaces of KRas, destabilizing the ARaf/KRas complex and thereby influencing downstream signaling transduction. SS-3091 has significant anticancer and antiproliferation activities against the KRas G12D, G12C, G12V, and G12S mutants in various cancer cells[1].
Molekulargewicht:
609.68
CAS Nummer:
[2756257-56-2]
Formel:
C36H34F3N5O
Target-Kategorie:
Ras
Anwendungsbeschreibung:
MCE Product type: Reference compound
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