JNJ-78911118 Preis auf Anfrage

Artikelnummer: MCE-HY-178121
Artikelname: JNJ-78911118 Preis auf Anfrage
Artikelnummer: MCE-HY-178121
Hersteller Artikelnummer: HY-178121
Alternativnummer: MCE-HY-178121-5MG,MCE-HY-178121-10MG,MCE-HY-178121-25MG
Hersteller: MedchemExpress
Kategorie: Biochemikalien
JNJ-78911118 is a potent, brain-penetrant, selective GluN2A antagonist (IC50 = 44 nM). JNJ-78911118 shows >200-fold selectivity against GluN1/2B, 2C and 2D receptors. JNJ-78911118 functions as a negative allosteric modulator (NAM) by insurmountably suppressing glutamate efficacy and reducing glycine potency at GluN1/2A receptors. JNJ-78911118 produces profound pharmacodynamic effects in vivo. JNJ-78911118 can be used for depression research[1].
Molekulargewicht: 419.81
Reinheit: 99.38
Formel: C19H16ClF2N5O2
Target-Kategorie: iGluR
Anwendungsbeschreibung: MCE Product type: Reference compound