SQS-IN-1 is a squalene synthase (SQS) inhibitor. SQS-IN-1 exhibits potent and broad-spectrum anti-proliferative effects on both mouse and human lung cancer cell lines. SQS-IN-1 inhibits DNA replication and the cell cycle, causing mitochondrial hyperpolarization and inducing cell apoptosis. SQS-IN-1 inhibits cell migration and invasion. SQS-IN-1 can be used to the study of lung cancer[1].
Molekulargewicht:
503.39
CAS Nummer:
[2306302-57-6]
Formel:
C24H27BrN2O5
Target-Kategorie:
Apoptosis,DNA/RNA Synthesis,Farnesyl Transferase
Anwendungsbeschreibung:
Reference compound
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