VHR-IN-7 is a selective vaccinia H1-related (VHR) phosphatase inhibitor with an IC50 of 71 nM. VHR-IN-7 shows very weaker inhibitory activity against MKP-1 (IC50 = 0.47 µM), CD45 (IC50 = 0.3 µM), Cdc25A (IC50 = 3.4 µM), PTP1B (IC50 = 0.59 µM), and HePTP (IC50 = 1.2 µM). VHR-IN-7 inhibits the proliferation of HeLa cells. VHR-IN-7 can be used for the research of cervical cancer[1].
Molekulargewicht:
612.14
CAS Nummer:
[1146616-17-2]
Formel:
C28H22ClN3O5S3
Target-Kategorie:
Phosphatase
Anwendungsbeschreibung:
MCE Product type: Reference compound1
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