VHR-IN-9 is a selective vaccinia H1-related (VHR) phosphatase inhibitor with an IC50 of 270 nM. VHR-IN-9 shows very weaker inhibitory activity against MKP-1 (IC50 = 2.8 µM), CD45 (IC50 = 1.8 µM), Cdc25A (IC50 = > 10 µM), PTP1B (IC50 = 2.2 µM), and HePTP (IC50 = 2.4 µM). VHR-IN-9 inhibits the proliferation of HeLa cells. VHR-IN-9 can be used for the research of cervical cancer[1].
Molekulargewicht:
618.77
CAS Nummer:
[1146616-18-3]
Formel:
C26H26N4O6S4
Target-Kategorie:
Phosphatase
Anwendungsbeschreibung:
MCE Product type: Reference compound
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