Tubulin-IN-57 is a Tubulin inhibitor. Tubulin-IN-57 is a potent antiproliferative agent that inhibits clonogenic formation, migration, and invasion of ovarian cancer cells. Tubulin-IN-57 inhibits tubulin polymerization, which in turn induces G2/M arrest and apoptosis in SKOV3 cells. Tubulin-IN-57 demonstrates potent antitumor activity without observable toxicity in an SKOV3 xenograft model. Y60S can be used for the study of ovarian cancer[1].
Molekulargewicht:
440.49
Formel:
C26H24N4O3
Target-Kategorie:
Apoptosis,Microtubule/Tubulin
Anwendungsbeschreibung:
MCE Product type: Reference compound
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