Debio 1453, CAS [[2422053-29-8]] Preis auf Anfrage
Artikelnummer:
MCE-HY-178347
Hersteller Artikelnummer:
HY-178347
Alternativnummer:
MCE-HY-178347-1UNIT
Hersteller:
MedchemExpress
Kategorie:
Biochemikalien
Debio 1453 is a bactericidal FabI inhibitor potent against N. gonorrhoeae (IC50 = 0.6 nM), including drug-resistant strains. Debio 1453 demonstrates a low propensity for resistance selection and is effective in eradicating both planktonic and intracellular bacteria through a mechanism of concurrently inhibiting FabI and engaging the non-mutable NADH cofactor. Debio 1453 clears antibiotic-resistant N. gonorrhoeae infection in a murine vaginal model. Debio 1453 can be used for gonorrhoea research[1].
Molekulargewicht:
420.46
CAS Nummer:
[2422053-29-8]
Formel:
C23H24N4O4
Target-Kategorie:
Bacterial
Anwendungsbeschreibung:
MCE Product type: Reference compound
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