CAII/VII-IN-1, CAS [[3085155-69-4]] Preis auf Anfrage
Artikelnummer:
MCE-HY-178362
Hersteller Artikelnummer:
HY-178362
Alternativnummer:
MCE-HY-178362-1UNIT
Hersteller:
MedchemExpress
Kategorie:
Biochemikalien
CAII/VII-IN-1 is an orally active hCA II (KI = 12.3 nM), and hCA VII (KI = 22.6 nM) inhibitor, showing no significant activity against hCA I. CAII/VII-IN-1 shows excellent neuroprotective activity in vivo Pilocarpine (HY-B0726A)-induced seizure model. CAII/VII-IN-1 can upregulate KCC2 and inhibit mTOR, exerting neuroprotective effects. CAII/VII-IN-1 does not show any significant neurotoxic effects or alterations in liver and kidney function. CAII/VII-IN-1 can be used for the study of epilepsy[1].
Molekulargewicht:
639.11
CAS Nummer:
[3085155-69-4]
Formel:
C27H23ClN8O5S2
Target-Kategorie:
Carbonic Anhydrase,mTOR,NKCC
Anwendungsbeschreibung:
MCE Product type: Reference compound
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