BGC1614 is a Nectin-4-targeting bicyclic toxin conjugate (BTC) belonging to the category of peptide-drug conjugates (PDCs). BGC1614 exhibits strong targeted binding ability to Nectin-4, with an KD of 3.859 * 10-7 M. BGC1614 exhibits superior antitumor efficacy in nude mice bearing PC-3 and N87 tumor xenografts. BGC1614 can be used for research related to Nectin-4-overexpressing tumors (such as prostate cancer, gastric cancer)[1].
Molekulargewicht:
8439.78
Formel:
C387H582N94O104S7
Target-Kategorie:
Nectin-4
Anwendungsbeschreibung:
MCE Product type: Reference compound
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