RET-IN-31, CAS [[2491726-04-4]] Preis auf Anfrage
Artikelnummer:
MCE-HY-178786
| Artikelname: |
RET-IN-31, CAS [[2491726-04-4]] Preis auf Anfrage |
| Artikelnummer: |
MCE-HY-178786 |
| Hersteller Artikelnummer: |
HY-178786 |
| Alternativnummer: |
MCE-HY-178786-1UNIT |
| Hersteller: |
MedchemExpress |
| Kategorie: |
Biochemikalien |
| RET-IN-31 (Compound 13) is an orally active, selective RET inhibitor (IC50s: 1.4 nM, 1.9 nM, 3.8 nM for RETWT, RETV804L, RETV804M, respectively). RET-IN-31 inhibits hERG and Cytochrome P450 (IC50s: 13.6 µM, 7.9 µM, 12.8 µM, 16.9 µM, 8.9 µM, 13.0 µM for CYP1A2, CYP2C9, CYP2C19, CYP2D6, CYP3A4-M, CYP3A4-T, respectively). RET-IN-31 has anti-cancer effects against activated RET mutations and gene fusion-driven cancers[1]. |
| Molekulargewicht: |
488.52 |
| CAS Nummer: |
[2491726-04-4] |
| Formel: |
C24H25FN10O |
| Target-Kategorie: |
Cytochrome P450,Potassium Channel,RET |
| Anwendungsbeschreibung: |
MCE Product type: Reference compound |
