FLT3-IN-35 (Compound 4K) is an orally active, covalent, irreversible FLT3 inhibitor. FLT3-IN-35 inhibits the phosphorylation of FLT3 and its downstream signaling factors, as well as induces cell cycle arrest and apoptosis. FLT3-IN-35 inhibits the phosphorylation of FLT3 and its downstream signaling factors, as well as induced cell cycle arrest and apoptosis. FLT3-IN-35 can be used for the study of acute myeloid leukemia (AML)[1].
Molekulargewicht:
478.59
Formel:
C29H30N6O
Target-Kategorie:
Apoptosis,FLT3
Anwendungsbeschreibung:
MCE Product type: Reference compound
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