APL-5125 (Compound 61f) is a potent, selective and orally active ATP-competitive CK2alpha inhibitor with an IC50 of 0.348 nM and a Ki of 0.095 nM. APL-5125 binds to CK2alpha in a bivalent manner, simultaneously interacting with the ATP-binding site and the alphaD pocket. APL-5125 exhibits antitumor activity and can be used for the research of cancer, such as colon cancer[1].
Molekulargewicht:
565.49
CAS Nummer:
[2830619-57-1]
Formel:
C27H24F5N3O5
Target-Kategorie:
Casein Kinase
Anwendungsbeschreibung:
MCE Product type: Reference compound
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