CAIX/XII-IN-16 Preis auf Anfrage

Produktübersicht

• Artikelname: CAIX/XII-IN-16 Preis auf Anfrage
• Artikelnummer: MCE-HY-179034
• Hersteller Artikelnummer: HY-179034
• Alternativnummer: MCE-HY-179034-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

CAIX/XII-IN-16 (Compound 5d) is a selective inhibitor of CA IX/XII and c-Met. CAIX/XII-IN-16's Ki values for hCA IX, hCA XII and CA I are 10.6, 31.8 and 2361 nM respectively, and its IC50 value for c-Met is 0.49 µM. CAIX/XII-IN-16 exhibits significantly enhanced cytotoxicity against colon cancer cells under hypoxic conditions. CAIX/XII-IN-16 causes cell cycle arrest and induces apoptosis (apoptosis). CAIX/XII-IN-16 significantly enhances the efficacy of Oxaliplatin (HY-17371) and 5-Fluorouracil (HY-90006). CAIX/XII-IN-16 can be used for studies on chemotherapy resistance related to hypoxia[1].

Produkteigenschaften

• Molekulargewicht: 439.45
• Formel: C19H17N7O4S
• Target-Kategorie: Apoptosis,Carbonic Anhydrase,c-Met/HGFR

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound