PROTAC BCL6/IKZF1/3 Degrader-1 is a selective and orally active BCL6 and IKZF1/3 PROTAC degrader. PROTAC BCL6/IKZF1/3 Degrader-1 exhibits superior antiproliferative effects in various germinal center B-cell-like (GCB) and activated B-cell-like (ABC) diffuse large B-cell lymphoma (DLBCL) cell lines. PROTAC BCL6/IKZF1/3 Degrader-1 can be used for the research of cancer, such as lymphoma[1]. (Structure Note: Pink: BCL6/IKZF1/3 ligand (HY-179064), Blue: CRBN ligand (HY-41547), Black: linker (HY-42427), CRBN ligand-Linker: (HY-179066))
Molekulargewicht:
853.36
Formel:
C43H49ClN10O7
Target-Kategorie:
BCL6,IKZF Family,PROTACs
Anwendungsbeschreibung:
MCE Product type: Reference compound
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